Manon Morin

Identifying candidate accessory domains by mining putative venom protein fusions

Rachel J. Dutton, Elizabeth A. McDaniel, and Manon Morin

Published: Aug 15, 2023

Hoping to find proteins that alter physiology in useful ways, we screened venom data sets for toxins fused to domains with additional functionality. We identified candidates, but struggled to infer any novel functions, and none seem well-conserved across venomous species.

Connections

Supplements (2): Code v2.0 - GitHub • Data - Zenodo

A structurally divergent actin conserved in fungi has no association with specific traits

Prachee Avasthi, Brae M. Bigge, Ilya Kolb, David G. Mets, Manon Morin, Austin H. Patton, and Ryan York

Published: Mar 06, 2024

We outline a comparative approach to investigate protein function by correlating the presence or absence of a protein with species-level phenotypes. We applied this strategy to a novel actin isoform in fungi but didn’t find an association with any of the phenotypes we considered.

Connections

Supplements (2): Data - Zenodo • Code v1.0 - GitHub

Creating a 7,000-strain E. coli genotype dataset with antimicrobial resistance phenotypes

David G. Mets and Manon Morin

Published: Aug 22, 2024

We assembled a comprehensive E. coli antimicrobial resistance phenotype-genotype resource. This dataset will aid large-scale genetic studies on anti-microbial resistance and support research in phylogenetics and other fields.

Connections

Supplements (2): Code v1.0 - GitHub • Data - Zenodo