Cameron Dale MacQuarrie

Arcadia Science, Scientist

Cell biologist studying the morphologies and behaviors of unique organisms.

Berkeley, CA, USA cdmacquarrie.com 0000-0001-9504-6375 https://github.com/Arcadia-Science cdmacquarrie cdmacquarrie in/cameron-dale-macquarrie-bbb89258/cdmacquarrie.bsky.social lGgNSvAAAAAJ&hl=en

All Pubs (6)Attributed Pubs (3)

Inducing protoplast formation in Phaeodactylum tricornutum by silica deprivation, enzymatic treatment, or cytoskeletal inhibition

Prachee Avasthi, Cameron Dale MacQuarrie, and Atanas Radkov

Published: Mar 29, 2023

Treating P. tricornutum cells with serine endopeptidases or certain cytoskeletal inhibitors induces the formation of cell wall-free protoplasts and suggests a novel role for actin and myosin in preventing protoplast formation.

Chlorarachniophytes form light- and Arp2/3 complex-dependent extensions that are involved in motility and predation

Prachee Avasthi and Cameron Dale MacQuarrie

Published: Dec 04, 2022

Long protrusions from several microalgal species appear to help cells move, capture prey, transport mitochondria and chloroplasts, and more. Are they filopodia that evolved abilities more like other actin- or microtubule-based structures, or are they something new?

Phenotypic differences between interfertile Chlamydomonas species

Prachee Avasthi, Ben Braverman, Tara Essock-Burns, Galo Garcia III, Cameron Dale MacQuarrie, David Q. Matus, David G. Mets, and Ryan York

Published: Jun 23, 2023

We’re crossing C. reinhardtii and C. smithii algae for high-throughput genotype-phenotype mapping. In preparation, we’re comparing the parents to uncover unique species-specific phenotypes.

Connections

Supplements (5): Code v3.0 - GitHub • Data - Cell wall experiments - Zenodo • Data - Focus-filtered time-lapse images and measurements - Zenodo • Data - High-res z-stacks - Zenodo • Protocol - Immobilizing cells for live imaging - protocols.io

ProteinCartography: Comparing proteins with structure-based maps for interactive exploration

Prachee Avasthi, Brae M. Bigge, Feridun Mert Celebi, Keith Cheveralls, Jase Gehring, Erin McGeever, Gilad Mishne, Atanas Radkov, and 1 more

Published: Sep 29, 2023

The ProteinCartography pipeline identifies proteins related to a query protein using sequence- and structure-based searches, compares all protein structures, and creates a navigable map that can be used to look at protein relationships and make hypotheses about function.

Connections

Supplements (3): ProteinCartography v0.5.0 - GitHub • ProteinCartography v0.4.2 - GitHub • Data - Zenodo

The phenotype-o-mat: A flexible tool for collecting visual phenotypes

Ben Braverman, David G. Mets, and Ryan York

Published: Apr 24, 2024

We’ve developed an easy-to-assemble apparatus and software for the automated collection of visible biological phenotypes such as growth, macroscopic morphology, motion, reflectance, and fluorescence.

Connections

Supplements (3): Code v1.0 - GitHub • Data - Zenodo • Protocol - Building a phenotype-o-mat: A low-cost DIY plate reader for high-throughput phenotype measurements - protocols.io

Raman spectroscopy enables rapid and inexpensive exploration of biology

Prachee Avasthi, Brae M. Bigge, Ben Braverman, Tara Essock-Burns, Ryan Lane, David G. Mets, Austin H. Patton, and Ryan York

Published: May 31, 2024

To test its utility in analyzing biological samples, we built an open-source Raman spectrometer and collected spectra from chilis, beer, and algae. We could stratify samples, classify replicates, and link spectra with quantitative traits of beer (ABV) and chilis (perceived heat).

Connections

Supplements (1): Code and data - GitHub