Brae M. Bigge

0000-0002-0907-4597 https://twitter.com/BiggeBrae https://scholar.google.com/citations?user=iOah-RkAAAAJ&hl=en

Defining actin: Combining sequence, structure, and functional analysis to propose useful boundaries

Prachee Avasthi, Brae M. Bigge, and Taylor Reiter

Published: Dec 01, 2022

The process of deciding whether a candidate actin homolog represents a “true” actin is tricky. We propose clear and data-driven criteria to define actin that highlight the functional importance of this protein while accounting for phylogenetic diversity.

Connections

Supplements (2): Code v2.0 - GitHub • Data outputs - Zenodo

Inducing protoplast formation in Phaeodactylum tricornutum by silica deprivation, enzymatic treatment, or cytoskeletal inhibition

Prachee Avasthi, Cameron Dale MacQuarrie, and Atanas Radkov

Published: Mar 29, 2023

Treating P. tricornutum cells with serine endopeptidases or certain cytoskeletal inhibitors induces the formation of cell wall-free protoplasts and suggests a novel role for actin and myosin in preventing protoplast formation.