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Published: May 31, 2024
We’re using the well-studied superfamily of small monomeric GTPases, the Ras GTPases, to evaluate our structure-based clustering tool, ProteinCartography. We’re seeking feedback on working with this protein family and determining which individual proteins to study.
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Supplements (1): Data - Zenodo
How can we biochemically validate protein function predictions with the deoxycytidine kinase family?
Published: May 31, 2024
The human deoxycytidine kinase, a member of the nucleoside salvage pathway, has been studied extensively. We’ll use this family to assess our structure-based protein clustering tool, ProteinCartography. We’d love feedback on how we might work with this protein for validation.
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Supplements (1): Data - Zenodo
Published: May 31, 2024
We aim to validate ProteinCartography, a tool for structure-based protein clustering, by evaluating two foundational hypotheses: that proteins within a cluster have similar functions and proteins in different clusters have differing functions.
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Published: Mar 29, 2024
How can we measure the true impact of science? We're seeking feedback on indicators of the utility and rigor of publications beyond traditional journal metrics. Your input will help shape the future of our publishing experiment.
Published: Mar 05, 2024
We’re seeking feedback on NovelTree, our modular phylogenomic workflow. We’d appreciate your insights into how we can improve gene family inference, incorporate protein structure predictions, and expand to whole-genome data as input.
Published: Dec 20, 2023
Since releasing our pub on polyphosphate-forming proteins in bacteria, we’ve noticed the community has similar problems studying this process in diverse organisms. We’re actively seeking feedback with a focus on advancing basic discoveries and useful tools in this space!
